Take Two's Bioshock 2 on the Xbox 360 barely beat out Wii's popular New Super Mario Brothers for the month of February, according to NPD.  Full Results here:

Data care of NPD Group

PlayStation 2 101.9K
PlayStation 3 360.1K
PSP 133.4K
Xbox 360 422.0K
Wii 397.9K
Nintendo DS 613.2K


BIOSHOCK 2* 360 TAKE 2 INTERACTIVE Feb-10 562.9K
NEW SUPER MARIO BROS. WII WII NINTENDO OF AMERICA Nov-09 555.6K 2
CALL OF DUTY: MODERN WARFARE 2* 360 ACTIVISION BLIZZARD Nov-09 314.3K 3
JUST DANCE WII UBISOFT Nov-09 275.4K 4
SPORTS RESORT W/ WII MOTION PLUS* WII NINTENDO OF AMERICA Jul-09 272.5K 5
CALL OF DUTY: MODERN WARFARE 2* PS3 ACTIVISION BLIZZARD Nov-09 252.8K 6
MASS EFFECT 2 360 ELECTRONIC ARTS Jan-10 246.5K 7
DANTE'S INFERNO: DIVINE EDITION PS3 ELECTRONIC ARTS Feb-10 242.5K 8
DANTE'S INFERNO 360 ELECTRONIC ARTS Feb-10 224.7K 9
HEAVY RAIN PS3 SONY Feb-10 219.3K 10